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Introduction of temozolomide into standard care in 2005 coincided with improvements in survival and a rapid increase in temozolomide prescribing.

RD-staging provided the greatest stage data completeness and alignment to AJCC-TNM for prostate cancers, followed by breast, then melanoma and lung cancers.

The annual number of prostate cancer cases diagnosed in Australia increased from 3,606 in 1982 to 20,065 in 2012. The number of incident prostate cancer cases is projected to rise to 25,283 in 2022.

One dose had comparable effectiveness as two or three doses in preventing high-grade disease in a high coverage setting. One dose vaccination may be a viable strategy when working towards the global elimination of cervical cancer.

The majority of smokers diagnosed with cancer continue to smoke beyond diagnosis, even in the context of an intention to quit and attempts to do so. Cancer survivors who smoke remain motivated to quit well beyond the initial diagnosis.

The probability of death for Australian cancer patients has decreased over the past three decades. However, there is still the need for continuing efforts to improve cancer prevention, diagnosis, and treatment.

The consistent association with educational attainment suggests low health literacy may play a role in a cancer of unknown primary diagnosis.

There was an increase in the incidence of colorectal cancer for people younger than 50 years for some jurisdictions, including Australia, which may be relating to changing prevalence of colorectal cancer risk factors (e.g. excess bodyweight) in younger populations.

Low self-rated health may be a flag for undiagnosed cancer, and an investigation of its clinical utility in primary care appears warranted.