Clinical trials and primary care
Increased awareness of clinical trials changes people’s attitudes and willingness to enrol. Participation in clinical trials can provide many benefits, including:
- helping people play an active role in their care
- the potential for earlier access to promising interventions that are not yet widely available
- supporting medical science advancements.
The role of GPs in clinical trials
Engaging in conversations with patients about the availability of trials, possible advantages and disadvantages of involvement, and how to enrol is essential to support informed decision-making about participation in research.
My patient has cancer... is a clinical trial an option?
The content below is taken from our information sheet for GPs about cancer clinical trials. You can also download the PDF version.
My patient has cancer... is a clinical trial an option?
The content below is taken from our information sheet for GPs about cancer clinical trials. You can also download the PDF version.
Download the information sheet for GPs about cancer clinical trials (PDF) >
Information for GPs about cancer clinical trials
- GPs are the first point of care for 85% of cancer diagnoses.[1]
- Many patients are unaware clinical trials are an option.
- Patients are interested in enrolling in clinical trials.
- GP awareness of clinical trials empowers patients to discuss trials with their specialist.
- Patients value their GP’s involvement in their care.
- Clinical trials may provide patients with access to new and potentially life-saving treatments and care.
- Cancer clinical trials are not only for patients who have exhausted all treatment options.
- Cancer clinical trial results benefit all people with cancer.
- Prevent cancer.
- Find and diagnose cancer.
- Manage symptoms of cancer.
- Treat cancer.
- Manage side effects of cancer treatment.
- Improve wellbeing (quality of life).
- Monitor cancer over a long period.
- People of any age are eligible.
- People with any cancer stage are eligible.
- Participation is voluntary.
- Participants can withdraw any time. They will receive the best available standard of care.
- Trials are approved by ethics committees to monitor safety and compliance to regulations.
- Patients remain in the care of their GP during a trial, ensuring continuity of overall health care.
- GPs communicate with the research team about their patient’s progress in a trial.
Possible advantages
- Treat or control the cancer and improve patient’s health.
- Access new treatments and care.
- Help discover new or better ways to treat cancer.
Possible disadvantages
- Tested treatment may not work.
- The participant may experience side effects.
- More tests and medical visits requiring more time, travel and parking costs.
To prepare for regulatory approval and integration into standard of care,clinical trials test the safety and efficacy of pharmaceuticals and other treatments. Clinical trial testing occurs across four common phases.
Go to australianclinicaltrials.gov.au/health-care-providers for useful resources on the following topics:
- Why talk to your patients about clinical trials.
- How to refer your patients for a clinical trial.
- How to talk to your patients about clinical trials.
- Canrefer: website search to identifycancer specialists and hospitals in NSW and ACT conducting trials: canrefer.org.au
- Recruiting cancer clinical trials in NSW: website search to identify cancer trials by cancer type and location
- ClinTrial Refer: website or app search for trials, including cancer trials. Download ClinTrial Refer app for mobile phone or tablet.
Helpful links
Discussing cancer clinical trials with patients
Referring to sites conducting cancer clinical trials
How to find recruiting cancer clinical trials
- Canrefer: Cancer Institute NSW website search to identify cancer specialists and hospitals in NSW and ACT conducting trials.
- Recruiting cancer clinical trials in NSW: Cancer Institute NSW website search to identify cancer trials by cancer type and location.
- ClinTrial Refer: Website or app search for trials, including cancer trials. Download ClinTrial Refer app for mobile phone or tablet.
- Australian Clinical Trials: Australian New Zealand Clinical Trials Registry of clinical trials.
- Role of Primary Care and the RACGP in Clinical Trials: A GP presentation about clinical trial recruitment in primary care and general practice.
- Community and Primary Health Care Network: The University of Sydney network building partnerships with the university, Primary Health Care organisations and the community.
- Primary Care Collaborative Cancer Clinical Trials Group (PC4): National support for the development of high quality cancer research in primary care.
Information for patients
- Clinical Trials Glossary: Basic terminology about clinical trials.
- Clinical trial information for multicultural communities: Information supporting multicultural communities, including in-language resources in Arabic, Chinese, Greek, Italian, Korean, Vietnamese and more.
- Taking part in a clinical trial: Information about what's involved during and after participation in a clinical trial.
- Considerations for taking part in a clinical trial: Information about benefits and risks of clinical trial participation, and questions to ask the clinical team.
- How do clinical trials progress?: Understanding phases of clinical trial research.
Get in touch
If you'd like more information regarding any information on this page, contact our clinical trials team at cinsw-clinicaltrials@health.nsw.gov.au.
1. Nunez C, Nair-Shalliker V, Sarich P, Sitas F, Bauman A. Modifiable lifestyle factors and cancer risk: An Evidence Check rapid review brokered by the Sax Institute (saxinstitute.org.au) for the Cancer Institute NSW, 2018. Available at: cancer.nsw.gov.au/how-we-help/reports-andpublications/modifiable-lifestyle-factors-and-cancer-risk
